RALPH F. WELLS, M.D.
The subject of antibiotic-related, nonstaphylococcal pseudomembranous colitis has appeared sporadically in the medical literature for more than 20 years (1). Most of the broad-spectrum antibiotics have been implicated at one time or another. A new concern with the problem is reflected in reports of cases in which lincomycin or its 7-deoxy, 7-chloro derivative, clindamycin, seems to be the causative agent. Clindamycin continues in wide use because of its efficacy against some Gram-negative anaerobes, notably Bacteroides species, and its value as an alternative antiobiotic agent for the penicillin-sensitive person with certain Gram-positive infections. Because pseudomembranous colitis may occur with other antibiotics
WELLS RF. Clindamycin-Associated Colitis. Ann Intern Med. 1974;81:547–548. doi: 10.7326/0003-4819-81-4-547
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Published: Ann Intern Med. 1974;81(4):547-548.
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