M. A. MISHKEL, M.D.
To the editor: The paper of Ginsberg and associates (1) describes the effect of moderate quantities of alcohol on plasma lipoproteins in normolipemic and hyperlipemic patients. The pathogenesis of the hyperlipidemia is complex, for alcohol, in moderate or excessive amounts, may produce or aggravate type IV, type V, and even type I hyperlipoproteinemia. Also, in the recovery phase of severe type V hyperlipoproteinemia, the lipoprotein electrophoretic pattern and ultracentrifugation frequently mimics type III hyperlipoproteinemia.
I wish to report a related finding that I have not seen described before: an elevation of alpha-lipoprotein cholesterol that appeared to be related to heavy
MISHKEL MA. Alcohol and Alpha-Lipoprotein Cholesterol. Ann Intern Med. ;81:564–565. doi: 10.7326/0003-4819-81-4-564_2
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Published: Ann Intern Med. 1974;81(4):564-565.
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