SEYMOUR HERSCHBERG, M.D.
To the editor: The article by Dunlap, James, and Hume (Ann Intern Med 80:470-476, 1974) suggests that the rapid reversal of neutropenia before the anemia in the first case may have been caused by a lesser need of granulocytes for copper or differences in cell kinetics, or both. If one accepts these explanations, one then has to seek a different explanation for the second case. The authors postulate that the patient in the second case had neutropenia without anemia because the copper stores were not sufficiently depleted to produce anemia. The explanations postulated for the first case, if correct, would
HERSCHBERG S. Copper, Anemia, and Neutropenia. Ann Intern Med. 1974;81:568. doi: 10.7326/0003-4819-81-4-568_1
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Published: Ann Intern Med. 1974;81(4):568.
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