WALLACE J. MULLIGAN, M.D.
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To the editor: Dr. Harold Israel's thoughtful urgings to discontinue isoniazid prophylaxis are the reflections of a physician who has dealt with tuberculosis firsthand for a long time. But a call to discontinue isoniazid prophylaxis across the board requires rethinking. In repeated studies in the Navy, in urban ghetto populations, among the Eskimos, and on Indian reservations, a salient feature emerges: to reduce the incidence of tuberculosis among poverty populations, especially in view of the lack of enthusiasm for BCG vaccine, there is no substitute for an intelligent isoniazid prophylaxis program. Tuberculosis continues to be an illness of poor populations
MULLIGAN WJ. Stop Use of Isoniazid?. Ann Intern Med. ;81:570. doi: 10.7326/0003-4819-81-4-570_1
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Published: Ann Intern Med. 1974;81(4):570.
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