MICHAEL J. REZA, M.D.; BENNET E. ROTH, M.D.; MARTIN A. POPS, M.D., F.A.C.P.; LEONARD S. GOLDBERG, M.D., F.A.C.P.
A patient with granulomatous enterocolitis proved by clinical and radiographic findings had essential, mixed (IgG-IgM) cryoglobulinemia. Histologic examination of the surgically resected ileum and proximal colon showed severe vasculitis without evidence of inflammatory bowel disease. The cryoglobulin isolated from the patient's serum consisted of IgG and IgM immunoglobulins and contained rheumatoid factor in a high titer. These findings suggest that the intestinal vasculitis was associated with, and perhaps a consequence of, essential cryoglobulinemia.
MICHAEL J. REZA, BENNET E. ROTH, MARTIN A. POPS, LEONARD S. GOLDBERG. Intestinal Vasculitis in Essential, Mixed Cryoglobulinemia. Ann Intern Med. 1974;81:632–634. doi: 10.7326/0003-4819-81-5-632
Download citation file:
Published: Ann Intern Med. 1974;81(5):632-634.
Gastroenterology/Hepatology, Rheumatology, Vasculitides.
Results provided by:
Copyright © 2017 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use