SANDOR A. FRIEDMAN, M.D., F.A.C.P.; HERMAN ROSEN, M.D., F.A.C.P.
Prolongation of life by maintenance hemodialysis has led to the discovery of several long-term uremic complications. The newest one is accelerated degenerative cardiovascular disease. Lindner and associates (1) reported, from a retrospective study of 39 patients (mean age, 37 years) who received hemodialysis in Seattle after 1960, a 56.4% mortality in a 13-year period. Fourteen of 23 deaths were due to cardiovascular disease, including myocardial infarction in 8 cases and strokes in 3. The cumulative incidence of coronary artery disease was 52.5% after 10 years, more than 20 times that expected for normal persons of similar age and even higher
FRIEDMAN SA, ROSEN H. Uremia and Cardiovascular Mortality. Ann Intern Med. ;81:696–697. doi: 10.7326/0003-4819-81-5-696
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Published: Ann Intern Med. 1974;81(5):696-697.
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