ALTON I. SUTNICK, M.D., F.A.C.P.; BARUCH S. BLUMBERG, M.D., D. PHIL., F.A.C.P.; EDWARD D. LUSTBADER, PH.D.
To the editor: Kolk-Vegter, Bosch, and van Leeuwen (1) described 11 patients with chronic renal disease treated at a hemodialysis unit in Amsterdam, The Netherlands. They developed anicteric hepatitis, with serum glutamic pyruvic transaminase (SGPT) elevations of over 150 units. In all but one, Australia antigen (hepatitis B surface antigen, HBSAg) was detected in the blood. All the patients had a spontaneous rise in hemoglobin level, and transfusion requirements were less than those of 34 other dialysis patients who did not have liver disease.
In 1965 we began evaluating patients with Down's syndrome and HBSAg and in 1966 found that
SUTNICK AI, BLUMBERG BS, LUSTBADER ED. Elevated Serum Iron Levels and Persistent Australia Antigen (HBSAg). Ann Intern Med. ;81:855–856. doi: 10.7326/0003-4819-81-6-855
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Published: Ann Intern Med. 1974;81(6):855-856.
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