MICHAEL H. GORDON, M.D.; LOUIS H. TIGER, M.D.; GEORGE E. EHRLICH, M.D., F.A.C.P.
Sjögren's syndrome has recently been added to the list of contraindications to chrysotherapy for rheumatoid arthritis. The proscription was based on a study of Sjögren's syndrome analyzing all clinical details, including allergies. A rather larger proportion of patients than expected had developed reactions, but there were few patients in that particular study. Review of our experience with 101 gold-treated patients, 60 of whom had rheumatoid arthritis alone and 41 of whom also had Sjögren's syndrome, suggests that, if anything, the patients who had Sjögren's syndrome tolerated chrysotherapy somewhat better. As progressive rheumatoid arthritis accompanied by Sjögren's syndrome falls into the category of disease most likely to benefit from chrysotherapy, we conclude that gold compounds should not be withheld from these patients.
MICHAEL H. GORDON, LOUIS H. TIGER, GEORGE E. EHRLICH. Gold Reactions Are Not More Common in Sjögren's Syndrome. Ann Intern Med. 1975;82:47–49. doi: 10.7326/0003-4819-82-1-47
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Published: Ann Intern Med. 1975;82(1):47-49.
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