ADAN GONZALEZ, M.D.; ROBERT SODERBLOM, M.D.; SIEGMUND TEICHMAN, M.D.
To the editor: In a recent paper Weisinger and associates (Ann Intern Med 81:440-447, 1974) postulate that the cause of the reversible nephrotic proteinuria in their obese patients is renal venous hypertension. We would like to comment on this view and to propose an alternative explanation of their findings.
Although it has been shown that progressive constriction of the renal veins leads to proteinuria (1), this is usually well under the range of nephrotic syndrome even when the venous pressure is increased four to five times normal. Second, the evidence that elevated renal vein pressure is the mechanism responsible for the
GONZALEZ A, SODERBLOM R, TEICHMAN S. Nephrotic Proteinuria in Obesity. Ann Intern Med. ;82:122. doi: 10.7326/0003-4819-82-1-122_1
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Published: Ann Intern Med. 1975;82(1):122.
Nephrology, Nephrotic Syndrome, Obesity, Urological Disorders.
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