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Recent years have seen major advances in the science of therapeutics that provide a more certain base for the art of drug therapy and the intellectual substance for the emerging discipline of clinical pharmacology. This second edition follows its predecessor by six years. Although the many helpful, illustrative examples cited have been brought up to date, the clarity of the first edition in exposition of the fundamental principles of structure activity relationships, pharmacokinetics, drug metabolism, toxicology, and pharmacogenetics has been retained. Also included are more specialized chapters on drug resistance and tolerance, chemical mutagenesis, carcinogenesis and teratogenesis, and drug development
Principles of Drug Action: The Basis of Pharmacology.. Ann Intern Med. ;82:130. doi: 10.7326/0003-4819-82-1-130_2
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Published: Ann Intern Med. 1975;82(1):130.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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