WILLIAM R. HARLAN, M.D.
The coexistence of xanthomas and hyperlipidemia so often signifies parallel development of arteriosclerosis that the present concept has not changed since Fagge (1) stated over 100 years ago: "Thus, it would be a matter of indifference whether we should speak of the cutaneous disease as an atheroma of the skin or of the arterial affliction as a xanthoma of the aorta." Occasionally, exceptions are found and are noteworthy because they may further delineate the pathogenesis of arteriosclerosis and xanthomas. The patient described here had plasma cell malignancy and associated hyperlipidemia and developed unusual mucosal xanthomas but no arterial lipid deposits
WILLIAM R. HARLAN. Gingival "Lipid Line" and Discordant Development of Xanthomas and Arteriosclerosis. Ann Intern Med. 1975;82:227–228. doi: 10.7326/0003-4819-82-2-227
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Published: Ann Intern Med. 1975;82(2):227-228.
Cardiology, Coronary Risk Factors, Dyslipidemia.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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