RALPH L. CAVALIERI
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To the editor: The prospective study of acromegaly and cardiovascular disorders reported by McGuffin and associates (Ann Intern Med 81:11-18, 1974) concludes with a treatment recommendation that seems unfounded. They state that acromegalic patients who do not have hypertension or cardiac disease should not be treated with aggressive modes of therapy (presumably radiation or surgery) to prevent these complications. As evidence they report that in their study of 57 acromegalics, 13 of whom had hypertension, a marked reduction in plasma growth hormone concentration did not influence the level of blood pressure, although they give no specific data. They also found
CAVALIERI RL. Acromegaly and Cardiovascular Disease. Ann Intern Med. ;82:429–430. doi: 10.7326/0003-4819-82-3-429_2
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Published: Ann Intern Med. 1975;82(3):429-430.
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