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The author's approach to a picture of renal function is laudable, one firmly based on an understanding of basic physical and chemical processes and of basic renal mechanisms. Toward this end he opens with the basic principles of aqueous solutions, pH, and membrane properties. Some oversimplifications have been defended on the basis that the text is intended to be concise; this approach may lead, however, to erroneous conclusions. For example, the mechanism of buffer systems is illustrated as a means to bring pH back to normal, but the fact that compensation is never totally complete in such a system is
The Kidneys and the Internal Environment.. Ann Intern Med. ;82:444. doi: 10.7326/0003-4819-82-3-444_1
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Published: Ann Intern Med. 1975;82(3):444.
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