L. FRED AYVAZIAN, M.D.
To the editor: In their paper "Repeated Immunization: Possible Adverse Effects," White, Adler, and McGann (1) report on less than 10% of 700 male employees at Fort Derrick who since 1956 had received multiple immunizations; despite some interesting minor laboratory abnormalities in this group, the authors conclude that chronic stimulation of the immunoglobulin-stimulating system in the human seems to cause no adverse effects, unlike amyloid disease, myeloma, and hypersensitivity reported in laboratory animals. As in a similar study referred to, that is, the soldiers receiving influenza vaccine, the subjects studied were always or almost always men well above adolescent age.
AYVAZIAN LF. Risks of Repeated Immunization. Ann Intern Med. ;82:589. doi: 10.7326/0003-4819-82-4-589_1
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Published: Ann Intern Med. 1975;82(4):589.
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