B. H. AVASHIA, M.D.
To the editor: In their paper on anaphylaxis from a product or products of ethylene oxide in January issue (Ann Intern Med 82:58-60, 1975), Dr. Poothullil and associates have observed that "previously documented complications of ethylene oxide have not generally been attributed to allergy."
I draw attention to a paper by Drs. Sexton and Henson (1). During this experiment three of the subjects became sensitized and developed itching and urticaria after exposure to ethylene oxide. The authors pointed out the ability of ethylene oxide to act as antigen by combining with body protein and elicit an allergic skin reaction.
B. H. AVASHIA. Ethylene Oxide: Allergic Response. Ann Intern Med. 1975;82:724. doi: 10.7326/0003-4819-82-5-724_1
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Published: Ann Intern Med. 1975;82(5):724.
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