KEITH S. HENLEY, M.D., F.A.C.P., F.R.C.P.; HENRY D. APPELMAN, M.D.
For this editorial we define chronic hepatitis as histologically documented, prolonged, inflammatory disease of the liver, generally sparing the intrahepatic bile ducts, and unassociated with a readily identifiable etiologic agent other than perhaps the hepatitis B antigen in tissue or serum. The words "active" or "aggressive" will be used synonymously in relation to the clinical, biochemical, or histopathologic manifestations.
Our objectives are  to describe briefly the spectrum encompassed by this term;  to emphasize that clinical, biochemical, and histopathologic features do not always coincide;  to provide a guide for the clinician through a confusing nomenclature; and  to
HENLEY KS, APPELMAN HD. The Fading Menace of Chronic Hepatitis. Ann Intern Med. ;82:840–841. doi: 10.7326/0003-4819-82-6-840
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Published: Ann Intern Med. 1975;82(6):840-841.
Gastroenterology/Hepatology, Liver Disease.
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