JOEL S. GREENBERGER, M.D.; DAVID S. ROSENTHAL, M.D.; WILLIAM C. MOLONEY, M.D.
To the editor: In a recent paper, Mir and associates (Ann Intern Med 82:54-57, 1975) propose that the hypokalemia that often occurs in association with acute myeloid leukemia may be unrelated to levels of serum or urine lysozyme. We wish to comment on their data and draw their attention to some work in an appropriate animal model.
In a study of 32 patients, the authors reported that of 18 patients with elevated serum lysozyme levels, only 9 became hypokalemic. Similarly, of 18 patients with elevated levels of urinary lysozyme, only 10 became hypokalemic. The reverse correlation showed that although 19
GREENBERGER JS, ROSENTHAL DS, MOLONEY WC. Hypokalemia in Leukemia. Ann Intern Med. ;82:854–855. doi: 10.7326/0003-4819-82-6-854
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Published: Ann Intern Med. 1975;82(6):854-855.
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