F. W. DANBY, F.R.C.P.(C)
To the editor: Tetracycline has for years carried the following notation in the Physicians' Desk Reference: "Food and some dairy products also interfere with absorption. Oral forms of tetracycline should be given one hour before or two hours after meals."
It distresses me to see the Center for Disease Control (1) recommending as proper use 0.5 g, four times daily by mouth. Without a caution attached, patients almost invariably take medications with meals or milk, reducing the efficacy tremendously. I would like to believe that all physicians take the trouble to properly instruct patients in this regard, but my experience
DANBY FW. Gonorrhea and Oral Tetracycline. Ann Intern Med. ;83:121. doi: 10.7326/0003-4819-83-1-121_1
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Published: Ann Intern Med. 1975;83(1):121.
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