STEPHEN C. COHEN, M.D.; NICHOLAS J. DIBELLA, M.D.; JOHN C. MICHALAK, M.D.
We have recently seen a 63-year-old man with mixed cell Hodgkin's disease who has been receiving multiple agent chemotherapy for difficult-to-control retroperitoneal disease. One of the agents the patient has received is adriamycin. After extravasation of adriamycin, the patient developed an erythematous lesion at the extravasation site, which ultimately necrosed, ulcerated, and slowly began to heal at about 1½ months after the accident. After this incident the patient received multiple courses of nitrogen mustard and vinblastine without apparent difficulty. Two months after the extravasation of adriamycin (at a time when the wound seemed well on its way to healing), another
COHEN SC, DIBELLA NJ, MICHALAK JC. Recall Injury from Adriamycin. Ann Intern Med. ;83:232. doi: 10.7326/0003-4819-83-2-232_1
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Published: Ann Intern Med. 1975;83(2):232.
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