PHILIP L. CIMO, M.D.
To the editor: In their recent paper (Ann Intern Med 83:190-196, 1975) Lackner and Karpatkin reported that many patients with the "easy bruising" syndrome have abnormal platelet function, increased percentages of megathrombocytes, and an elevated prevalence of antiplatelet antibody. I agree that the easy bruising in these patients reflects a qualitative platelet defect, but I question whether the defect is the result of an autoimmune process. Most of the patients studied were women of child-bearing age and, unless the target platelets used for platelet antibody testing were autologous, the increased frequency of platelet antibody activity could be explained by the
CIMO PL. Antiplatelet Antibody. Ann Intern Med. ;83:738. doi: 10.7326/0003-4819-83-5-738_1
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Published: Ann Intern Med. 1975;83(5):738.
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