ROGER P. SMITH, PH.D.; ROBERT E. GOSSELIN, M.D., PH.D.; ROBERT KRUSZYNA, M.S.
To the editor: Since we (RS, RG) were responsible for the suggestion that the therapeutic induction of methemoglobinemia might be of value in acute azide poisoning (1, 2), we are naturally disappointed that it was not effective in its first human trial (3). That recommendation will not appear in the fourth edition of our reference manual, which is now in press (2).
Recent observations by one of us (RK) suggest that there are two distinctive mechanisms of death in mice acutely poisoned by sodium azide. If death in convulsions does not occur within 10 minutes, survivors may die during the
SMITH RP, GOSSELIN RE, KRUSZYNA R. Sodium Azide Poisoning. Ann Intern Med. ;83:739. doi: 10.7326/0003-4819-83-5-739_1
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Published: Ann Intern Med. 1975;83(5):739.
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