Y. HERISHANU, M.D.; P. ROSENBERG, MB.CH.B.
Propranolol and other adrenergic β-blocking agents are widely used in medicine. Side effects such as hypotension, worsening or precipitation of congestive heart failure, or asthma are well known.
In-vitro experiments by workers such as Werman and Wislicki (1) and Wislicki and Rosenblum (2) have shown that β-blockers are capable of a depressant effect on the neuromuscular junction.
We saw three patients in whom it seemed to us that this phenomenon played an important role.
Patient 1 was a woman aged 67 years who, because of hypertension, was receiving oxprenolol (Trasicor⌖), 30 mg/day. For 3 months before her appearance in our
HERISHANU Y, ROSENBERG P. β-Blockers and Myasthenia Gravis. Ann Intern Med. ;83:834–835. doi: 10.7326/0003-4819-83-6-834
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Published: Ann Intern Med. 1975;83(6):834-835.
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