RONALD D. BROWN, M.D., F.A.C.P.; JANICE DOUGLAS, M.D.
Several black patients were referred for evaluation of suspected Graves' disease, mainly based upon the finding of exophthalmos. Exophthalmometry showed readings above the published normal range (1-3). All of these patients, however, were clinically euthyroid and none had elevated serum thyroxine (column), or protein-bound iodine levels, or increased thyroidal uptake of radioactive iodine. Following administration of triiodothyronine, 75 µg for 7 to 10 days, the thyroidal uptake of radioactive iodine clearly decreased making the diagnosis of Graves' disease without hyperthyroidism unlikely (4). We suspected that a proportion of black individuals normally have more protrusion of their eyes than whites, but
BROWN RD, DOUGLAS J. Exophthalmometry of Blacks. Ann Intern Med. ;83:835–836. doi: 10.7326/0003-4819-83-6-835_2
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Published: Ann Intern Med. 1975;83(6):835-836.
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