MARK R. STEIN, M.D.; SHELDON L. SPECTOR, M.D., F.A.C.P.
To the editor: The recent paper by Shim and Williams, "Cardiac Response to Repeated Doses of Isoproterenol Aerosol" (Ann Intern Med 82:208-211, 1975), suggests that the frequent administration of aerosolized isoproterenol has no harmful effects in asthmatics. We wonder if this suggestion is justified by their data. Regarding patient selection, the designation of "moderate-to-severe asthma" based on the patient's subjective assessment of himself is not in keeping with the clinical data and is not the usual way of categorizing severity. Patients 4, 5, and 10 were on no corticosteroids and Patients 7, 8, and 13 were on no medications at
MARK R. STEIN, SHELDON L. SPECTOR. Isoproterenol, Asthma, and the Heart. Ann Intern Med. 1975;83:908–909. doi: 10.7326/0003-4819-83-6-908_2
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Published: Ann Intern Med. 1975;83(6):908-909.
Asthma, Cardiology, Pulmonary/Critical Care.
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