FRANK C. ARNETT JR., M.D.
The paper by Cohen and colleagues in this issue of the Annals brings into sharp focus the importance of the association of the histocompatibility antigen, HL-A W27, with the spondylitic group of diseases. Their data show that the prevalence of spondylitis may far exceed the 0.4% previously estimated and may actually approach 1% to 2%, a figure comparable to that for rheumatoid arthritis (1). Another recent study supports this same high frequency of "spondylitis stigmata" in "apparently healthy" W27-positive male blood donors but additionally reports a similar risk for women (2). From these studies it would appear that spondylitis has
ARNETT FC. The Implications of HL-A W27. Ann Intern Med. ;84:94–95. doi: 10.7326/0003-4819-84-1-94
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Published: Ann Intern Med. 1976;84(1):94-95.
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