DAVID W. FRASER, M.D.
Two-thirds of recent tetanus cases in this country have followed puncture wounds, lacerations, and crush injuries (1-3). These are the cases that the physician caring for the wounded patient seeks to prevent. Rapid, thorough debridement continues to be of central importance in treating the wound to prevent proliferation of Clostridium tetani. Guidelines for administering passive and active immunization to the injured patient have evolved during the past two decades with our increasing knowledge of the immune response to fluid and adsorbed tetanus toxoid and with the introduction of human tetanus immune globulin. Smith, Laurence, and Evans (4) recently published revised
FRASER DW. Preventing Tetanus in Patients with Wounds. Ann Intern Med. ;84:95–97. doi: 10.7326/0003-4819-84-1-95
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Published: Ann Intern Med. 1976;84(1):95-97.
Emergency Medicine, Infectious Disease.
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