HERBERT R. DYER, M.D.
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To the editor: Since the original articles on new drugs very rarely give accurate information as to what the final usefulness of the drug in disease treatment will be, a longer term follow-up on naproxen in rheumatoid arthritis may be useful to your readers.
Of 15 patients begun in the naproxen study reported in the October issue (Ann Intern Med 83:470-475, 1975), 4 got better on placebo during the washout period. Seven patients took naproxen. A 60-year-old man who had previously been well maintained on aspirin died of an acute myocardial infarction several weeks after starting thestudy and being changed
DYER HR. Naproxen Follow-Up. Ann Intern Med. ;84:221. doi: 10.7326/0003-4819-84-2-221_1
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Published: Ann Intern Med. 1976;84(2):221.
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