ROY A. KAPLAN, M.D.
To the editor: In their recent review on lithium salts, Baldessarini and Lipinski (1) mentioned leukocytosis as a side effect of therapy. They commented, "The leukocytosis is often persistent, but is fully reversible and is not known to be of any particular clinical significance at the present time." However, a recent report (2) suggests that lithium is helpful in patients with Felty's syndrome.
In their study, Gupta, Robinson, and Smyth (2) treated 10 patients with Felty's syndrome with lithium carbonate, Li2 CO3, orally for 6 weeks in doses of either 600 mg/day or 900 mg/day. All patients on the higher
KAPLAN RA. Lithium in Felty's Syndrome. Ann Intern Med. ;84:342. doi: 10.7326/0003-4819-84-3-342_1
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Published: Ann Intern Med. 1976;84(3):342.
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