JOHN J. STUART, M.D.; HAROLD R. ROBERTS, M.D.
To the editor: The recent paper by Targan, Chassin, and Guze (1) reporting a case of Dilantin-induced disseminated intravascular coagulation prompts us to report a similar
case in which isoniazid was the offending drug.
A 58-year-old black woman was admitted to another hospital on 11 October 1975 because of syncope and fever. Six months previously, she had been placed on prednisone for rheumatoid lung disease. A chest X ray showed marked chronic obstructive lung disease and infiltrates in the right upper and lower lobes. Several sputum smears were positive for acid-fast organisms, later identified as Mycobacterium intracellulare. She was begun
STUART JJ, ROBERTS HR. Isoniazid and Disseminated Intravascular Coagulation. Ann Intern Med. ;84:490–491. doi: 10.7326/0003-4819-84-4-490_3
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Published: Ann Intern Med. 1976;84(4):490-491.
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