MICHAEL A. VANCE, M.S., R.PH.; WILLIAM R. MILLINGTON, M.S., R.PH.
To the editor: In light of our recent experiences we found particularly interesting the report by Ray and associates (1) that 20 of 3409 physicians accounted for 55% of chloramphenicol prescriptions in their study. The 1973 death of a young woman from aplastic anemia after chloramphenicol therapy at a Boston area hospital had prompted us to look at in-hospital use of this drug. We reviewed antibiotic use by auditing antibiotic drug orders and interviewing pharmacists employed in several hospitals in Boston and surrounding areas. We found, in three hospitals, that chloramphenicol was overused and that much of this excess was
MICHAEL A. VANCE, WILLIAM R. MILLINGTON. Prescribing of Chloramphenicol. Ann Intern Med. 1976;85:125. doi: 10.7326/0003-4819-85-1-125_1
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Published: Ann Intern Med. 1976;85(1):125.
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