GENE V. BALL, M.D., F.A.C.P.; LAWRENCE N. GOLDMAN, M.D.
Necrotizing skin lesions developed in a man with chronic ulcerative colitis. No evidence of intrinsic disease of medium or small-sized vessels was found. A circulating cryofibrinogen was thought to be responsible for in situ thrombosis leading to skin infarctions. Sodium warfarin in a daily dose of 2.5 to 5 mg appears to have thwarted progression of developing lesions and the occurrence of new ones.
GENE V. BALL, LAWRENCE N. GOLDMAN. Chronic Ulcerative Colitis, Skin Necrosis, and Cryofibrinogenemia. Ann Intern Med. 1976;85:464–466. doi: 10.7326/0003-4819-85-4-464
Download citation file:
Published: Ann Intern Med. 1976;85(4):464-466.
Gastroenterology/Hepatology, Inflammatory Bowel Disease.
Results provided by:
Copyright © 2017 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use