GENE V. BALL, M.D., F.A.C.P.; LAWRENCE N. GOLDMAN, M.D.
Necrotizing skin lesions developed in a man with chronic ulcerative colitis. No evidence of intrinsic disease of medium or small-sized vessels was found. A circulating cryofibrinogen was thought to be responsible for in situ thrombosis leading to skin infarctions. Sodium warfarin in a daily dose of 2.5 to 5 mg appears to have thwarted progression of developing lesions and the occurrence of new ones.
BALL GV, GOLDMAN LN. Chronic Ulcerative Colitis, Skin Necrosis, and Cryofibrinogenemia. Ann Intern Med. ;85:464–466. doi: 10.7326/0003-4819-85-4-464
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Published: Ann Intern Med. 1976;85(4):464-466.
Gastroenterology/Hepatology, Inflammatory Bowel Disease.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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