ANTHONY N. DEMARIA, M.D.
The clinical manifestations of the mitral valve prolapse syndrome, which was long thought to be an obscure, infrequently encountered disorder, have become recognized with increasing frequency. Auscultatory abnormalities of mitral valve prolapse have been recognized, for example, in as many as 17% of asymptomatic female patients during screening examinations (1). Indeed, so frequently has auscultatory, echocardiographic, or cineangiographic evidence of the syndrome been found in asymptomatic persons without other evidence of heart disease, that clinical significance of the abnormalities thus detected has come into question. Nevertheless severe complications, presumably related to mitral valve prolapse, have been seen to occur in
DEMARIA AN. The Syndrome of Mitral Valve Prolapse: Problems and Perspectives. Ann Intern Med. ;85:525–526. doi: 10.7326/0003-4819-85-4-525
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Published: Ann Intern Med. 1976;85(4):525-526.
Cardiology, Valvular Heart Disease.
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