J. H. GASKIN, M.D.
To the editor: The paper, "Thyroid Dysfunction in Uremia: Evidence for Thyroid and Hypophyseal Abnormalities," by Ramirez and colleagues (Ann Intern Med 84:672-676, 1976), addresses an important clinical problem. However, it seems to confirm a statement in a recent review (1) that "it is not surprising that studies of thyroid gland function in chronic renal failure are confusing."
The finding of impaired thyrotrophin (TSH) release after thyrotrophin-releasing hormone (TRH) stimulation conflicts with their eariler findings (2), as they noted, and with the findings of others (3). Two of their four patients with renal failure in the earlier study would have
GASKIN JH. Thyroid Gland and Uremia. Ann Intern Med. ;85:680–681. doi: 10.7326/0003-4819-85-5-680
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Published: Ann Intern Med. 1976;85(5):680-681.
Endocrine and Metabolism, Nephrology, Thyroid Disorders.
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