ARNOLD S. BERNS, M.D.; KENNETH R. KOLLMEYER, PH.D.
Depression of sinoatrial and atrioventricular conduction due to severe hypermagnesemia (serum magnesium concentration, 10 to 15 meq/litre) has been previously well documented (1-3). We recently had the opportunity to observe a patient with chronic renal insufficiency who showed severe junctional bradycardia associated with mild hypermagnesemia (serum magnesium concentration, 3.3 to 4.8 meq/litre). We wish to emphasize the association between mild elevations in serum magnesium concentration and clinical cardiotoxicity.
A 62-year-old woman was admitted to Colorado General Hospital for the evaluation of hematemesis and melena. Past medical history included diabetes mellitus since age 50, lumbosacral osteoarthritis, hypertension, and peripheral vascular disease.
BERNS AS, KOLLMEYER KR. Magnesium-Induced Bradycardia. Ann Intern Med. 1976;85:760–761. doi: 10.7326/0003-4819-85-6-760
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Published: Ann Intern Med. 1976;85(6):760-761.
Cardiology, Rhythm Disorders and Devices.
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