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Pernicious anemia was a serious, frequently fatal disease until the discovery in 1926 that liver therapy could control it completely. This monograph, published in the 50th anniversary year of that discovery, attempts "to place the pathophysiological and pathogenetic aspects of pernicious anemia into a contemporary perspective." The emphasis, however, is heavily historical. More than 10% of the 446 references are from before 1900. Extensive space is given to the discovery of liver therapy and includes fascinating copies of the hospital chart of the first patient treated. First-person narratives of this treatment and of the purification and crystallization of the active
Pernicious Amenia. Volume 7 in the series Major Problems in Internal Medicine.. Ann Intern Med. 1976;85:836–837. doi: 10.7326/0003-4819-85-6-836_2
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Published: Ann Intern Med. 1976;85(6):836-837.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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