BURTON C. WEST, M.D., F.A.C.P.
To the editor: The diagnosis of sarcoidosis remains problematic despite recent reports of success with transbronchial biopsy (1, 2). These papers raise questions not raised by the authors: what etiologic assumptions underlie our diagnostic approach? What is an adequate working definition of sarcoidosis? The demonstration of noncaseating granulomas on transbronchial biopsies of selected patients is technically satisfying, but even with the refinements described by the authors, this is not an adequate definition. What is considered sarcoidosis by practical physicians might better be termed noncaseating granulomatous disease of unknown cause (3) in light of two reports of extensive searches for infectious
WEST BC. Diagnosis of Sarcoidosis. Ann Intern Med. ;86:241–242. doi: 10.7326/0003-4819-86-2-241_3
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Published: Ann Intern Med. 1977;86(2):241-242.
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