ROBERT T. EAGAN, M.D.; ROBERT E. LEE, M.D.; DAVID T. CARR, M.D.
To the editor: We read with interest the report by Greco and associates (1) on the enhanced skin and esophageal radiation reaction in small-cell lung cancer patients being treated with a three-drug combination chemotherapy program, including adriamycin (doxorubicin) at a dose of 40 mg/m2 followed by super voltage radiation. We are also aware of the reports by Donaldson, Glick, and Wilbur (2) and Cassady and associates (3). In light of the earlier reports, we have been closely observing our patients for similar reactions.
Our approach to therapy has been an adriamycin-based combination chemotherapy regimen administered concomitantly with radiation therapy. The
ROBERT T. EAGAN, ROBERT E. LEE, DAVID T. CARR. Adriamycin and Radiation Reaction. Ann Intern Med. 1977;86:243–244. doi: 10.7326/0003-4819-86-2-243
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Published: Ann Intern Med. 1977;86(2):243-244.
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