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Zinc has been known to be essential to life since 1869, when it was shown to be required by Aspergillus niger, but not until the past 15 years has its role in human health and disease begun to unfold. We are beginning to see that it has fundamental importance in many diseases through secondary or conditioned zinc deficiency. Moreover, although primary, or dietary, zinc deficiency has been conclusively identified in Iran and Egypt, Hambidge and his colleagues have shown that zinc deficiency in infants and young children is not uncommon in the United States. Other aspects of zinc metabolism have
Trace Elements in Human Health and Disease. Volume 1. Zinc and Copper.. Ann Intern Med. ;86:248–249. doi: 10.7326/0003-4819-86-2-248_2
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Published: Ann Intern Med. 1977;86(2):248-249.
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