MARTIN JEFFREY FRANK, M.D.
To the editor: The recent letter by Nixon and colleagues "Myocardial Infarction in Men in the Third Decade of Life" (Ann Intern Med 85:759-760, 1976), was thought-provoking. Six of the eight patients were cigarette smokers. Among these six patients, there were three with angiographic normal coronary arteries.
There may be a causal relation between cigarette smoking and those young men with myocardial infarction and radiographically patent coronary arteries. Smoking may induce coronary artery spasm to produce a myocardial infarction; when a patient is studied after infarction, the spasm subsides and the vessels appear normal.
Khan and Haywood (1) mention coronary
FRANK MJ. Smoking and Myocardial Infarction. Ann Intern Med. 1977;86:509. doi: 10.7326/0003-4819-86-4-509_1
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Published: Ann Intern Med. 1977;86(4):509.
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