CONRAD C. SIMPFENDORFER, M.D.
To the editor: Having read the editorial by Amorosi and Karpatkin (Ann Intern Med 86:102-106, 1977), I wish to report the case of a patient with thrombotic thrombocytopenic purpura in which antiplatelet agents played a major role in achieving a remission.
A 48-year-old woman was admitted to St. Luke's Hospital on 19 September 1974 with a 2-week history of progressive weakness and malaise.
At admission she appeared confused and restless. Laboratory findings included hemoglobin, 6.9 g/dl; hematocrit, 22%; leukocyte count, 24 600/mm3; platelets, 105 000/mm3; Coombs' test, negative; and prothrombin time, 11/11.8 sec. Urine and two blood cultures grew Escherichia
SIMPFENDORFER CC. Therapy for Thrombotic Thrombocytopenic Purpura. Ann Intern Med. 1977;86:657–659. doi: 10.7326/0003-4819-86-5-657_2
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Published: Ann Intern Med. 1977;86(5):657-659.
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