ANTTI ARO, M.D.; RISTO PELKONEN, M.D.; ARTO SIVULA, M.D.
To the editor: In the December 1976 issue Pak and Townsend (1) questioned the usefulness of the serum chloride/phosphate ratio in the diagnosis of primary hyperparathyroidism. Our experience indicates that the measurement of serum chloride and phosphate concentrations is of diagnostic value in hypercalcemia, even though the chloride/phosphate ratio has proved ineffective also in our practice.
We recently studied a series of 64 patients with hypercalcemia for a review article published in Finnish (2). Included were 40 patients with surgically proven primary hyperparathyroidism, 17 with malignant disease, most of them with skeletal involvement, four with vitamin D intoxication, and three
ARO A, PELKONEN R, SIVULA A. Hypercalcemia: Serum Chloride and Phosphate. Ann Intern Med. ;86:664. doi: 10.7326/0003-4819-86-5-664_1
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Published: Ann Intern Med. 1977;86(5):664.
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