TETSURO SHINDO, M.D.; CHIKARA SAKAI, M.D.; AKIRA SHIBATA, M.D.
Neutrophilic leukemia is characterized by leukocytosis with mature neutrophils in peripheral blood, absense of Ph′ chromosome, and elevated neutrophil alkaline phosphatase activity (1-4). Because it is occasionally difficult to rule out the leukemoid reaction, its disease entity is unestablished yet. To our knowledge, this is the first such case terminating in blastic crisis.
A 74-year-old man consulted a doctor with the complaint of impaired vision in January 1975. A diagnosis of senile cataract was made but he was found in leukocytosis and hepatosplenomegaly. He was subjectively so well that no specific treatment was done, and the course was observed as
SHINDO T, SAKAI C, SHIBATA A. Neutrophilic Leukemia and Blastic Crisis. Ann Intern Med. 1977;87:66–67. doi: 10.7326/0003-4819-87-1-66
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Published: Ann Intern Med. 1977;87(1):66-67.
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