ROBERT M. CRAIG, M.D.
To the editor: I was surprised to read that both patients described by Griner, Elbadawi, and Packman (1) who had veno-occlusive disease of the liver after chemotherapy of acute leukemia also had a low protein ascites ("characteristics of a transudate"). What were the ascitic fluid albumin, protein, and LDH values and the ascitic fluid to plasma ratios of these proteins? In veno-occlusive disease of the liver, I should expect a high protein ascites, with exuding of high protein lymph from the hepatic surface, a phenomenon well characterized by Witte and associates (2).
CRAIG RM. Ascitic Fluid in Veno-Occlusive Disease of the Liver. Ann Intern Med. ;87:246–247. doi: 10.7326/0003-4819-87-2-246_3
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Published: Ann Intern Med. 1977;87(2):246-247.
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