GIUSEPPE REMUZZI, M.D.; MANUELA LIVIO, M.D.; MARIA BENEDETTA DONATI, M.D., PH.D.; GIOVANNI DE GAETANO, M.D., PH.D.
To the editor: Segal and Weintraub (1) have reported a patient with Hashimoto's thyroiditis, myasthenia gravis, and autoimmune thrombocytopenic purpura. They suggested that the association of these three autoimmune disorders in the same patient might be due to a single pathogenetic mechanism and concluded that a defect in immunologic response could make a selected population more liable to develop certain autoimmune disorders.
We have recently seen a patient with myasthenia gravis and autoimmune thrombocytopenia and have discussed the possibility that the same genetic marker might be involved in the predisposition to both disorders (2).
The patient is a 29-year-old woman
REMUZZI G, LIVIO M, DONATI MB, DE GAETANO G. Myasthenia Gravis, Thrombocytopenia and HLA Antigens. Ann Intern Med. ;87:250–251. doi: 10.7326/0003-4819-87-2-250_3
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Published: Ann Intern Med. 1977;87(2):250-251.
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