LAWRENCE F. LAYFER, M.D.; ROBERT KATZ, M.D.; HARVEY GOLDEN, M.D.
To the editor: In a recent letter (Ann Intern Med 85:616-619, 1976), Ballou and associates present a case of diffuse intervertebral disc calcification associated with local infiltration of amyloid. They note that disc calcification was previously thought to be "highly suggestive, if not pathognomonic, of ochronosis," and speculate that other infiltrative processes may similarly lead to calcification at these sites.
Although not generally appreciated, intervertebral disc calcification has been reported in a number of other diseases. It is an infrequent, but by no means unusual, site of involvement in calcium pyrophosphate dihydrate deposition states. It has been reported in both
LAYFER LF, KATZ R, GOLDEN H. Diffuse Intervertebral Disc Calcification. Ann Intern Med. ;87:252. doi: 10.7326/0003-4819-87-2-252_1
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Published: Ann Intern Med. 1977;87(2):252.
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