WILLIAM M. BENNETT, M.D., F.A.C.P.; CHARLES PLAMP, M.D.; GEORGE A. PORTER, M.D.
The major clinical presentations of disease to a nephrologist can be grouped into six general areas: acute renal failure, chronic renal failure, nephrotic syndrome, fluid-electrolyte disorders, acid-base disturbances, and the uremic symptom-complex. Each of these major clinical syndromes can be caused by, or related to, drugs or environmental toxins. Prototype drugs can be used to highlight the features of each drug-related syndrome. Although it is preventable, drug-related disease may present opportunities to learn about general pathophysiologic mechanisms in clinical nephrology.
WILLIAM M. BENNETT, CHARLES PLAMP, GEORGE A. PORTER. Drug-Related Syndromes in Clinical Nephrology. Ann Intern Med. 1977;87:582–590. doi: 10.7326/0003-4819-87-5-582
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Published: Ann Intern Med. 1977;87(5):582-590.
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