STEPHEN J. LERMAN, M.D.; MARCIA R. SILVER, M.D.; GEORGE A. NANKERVIS, PH.D., M.D.
To the editor: In a paper on our 1969 clinical trial of HPV-77:DE-5 live attenuated rubella virus vaccine in adolescent girls and young women (1), we described in detail a 17-year-old vaccinee (subject #281) who developed moderate arthralgia of her knees and hips, moderate-to-severe arthritis of her fingers, and a painful ganglion. We noted that intermittent arthralgia of her knees and hips had persisted for a year after vaccination. We report here an 8-year follow-up.
Subject #281 is now a 25-year-old resident in internal medicine. At 2-to-3-month intervals and in association with the onset of cool, damp weather, she experiences
STEPHEN J. LERMAN, MARCIA R. SILVER, GEORGE A. NANKERVIS. Arthralgia and Rubella Immunization. Ann Intern Med. 1978;88:131. doi: 10.7326/0003-4819-88-1-131_1
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Published: Ann Intern Med. 1978;88(1):131.
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