L. A. WEINRAUCH, M.D.; J. A. D'ELIA, M.D., F.A.C.P.; R. W. HEALY, M.D.; R. E. GLEASON, Ph.D.; F. J. TAKACS, M.D., F.A.C.P.; J. A. LIBERTINO, M.D., F.A.C.S.; O. S. LELAND Jr., M.D.
Twenty-one juvenile-onset diabetic patients with azotemic nephropathy underwent coronary angiography and left ventriculography before renal transplantation or chronic hemodialysis. Two-year survival of 12 patients with no coronary artery disease (group A) was 88% compared to 22% for nine patients with coronary artery disease (group B) (P < 0.025). Each group A patient underwent renal transplantation (nine live-related, three cadaveric). Four group B patients received cadaveric allografts. Among group A patients two cadaveric allografts functioned while in group B patients no allografts were successful. In the absence of coronary artery disease, results were similar to those reported for nondiabetic persons. In the presence of coronary artery disease, 62% of the deaths were due to myocardial infarction or sudden death. These results indicate that atherosclerotic coronary artery disease is a major determinant of survival in diabetic patients undergoing chronic hemodialysis or renal transplantation.
WEINRAUCH LA, D'ELIA JA, HEALY RW, GLEASON RE, TAKACS FJ, LIBERTINO JA, et al. Asymptomatic Coronary Artery Disease: Angiography in Diabetic Patients Before Renal Transplantation: Relation of Findings to Postoperative Survival. Ann Intern Med. ;88:346–348. doi: 10.7326/0003-4819-88-3-346
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Published: Ann Intern Med. 1978;88(3):346-348.
Cardiology, Coronary Heart Disease, Coronary Risk Factors, Diabetes, Endocrine and Metabolism.
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