DANIEL C. POSTELLON, M.D.
To the editor: I wish to suggest an alternate or contributing mechanism for the transient postpartum hypothyroidism described by Amino and co-workers in the August 1977 issue (Ann Intern Med 87:155-159, 1977). Sack, Amado, and Lunenfeld have described the changes in secretion of thyroxine in breast milk (1). The amount secreted after the first postpartum week was substantial, estimated at about one half of the daily adult production rate. The concentration of thyroxine varied from patient to patient and from day to day but gradually decreased with decreasing milk production.
I assume that most of the patients with postpartum hypothyroidism
POSTELLON DC. Postpartum Hypothyroidism. Ann Intern Med. ;88:431–432. doi: 10.7326/0003-4819-88-3-431_3
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Published: Ann Intern Med. 1978;88(3):431-432.
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