DARIUS SAGHAFI, M.D.
To the editor: Ravid, Robson, and Kedar (Ann Intern Med 87:568-570, 1977) have reported a good response to prolonged colchicine therapy in four patients with amyloidosis associated with nephrotic syndrome. There was a previous report of improvement of secondary amyloid renal disease after appropriate therapy of the primary disease (1) and a well-documented case of primary amyloidosis with renal involvement that resolved after treatment with combined prednisone and chemotherapy (2). With the exception of lipoid nephrosis and diffuse proliferative lupus nephritis, and possibly idiopathic membranous nephritis, there is not any specific treatment available for nephrotic syndrome of other causes (3-5).
SAGHAFI D. Renal Amyloidosis?. Ann Intern Med. ;88:433–434. doi: 10.7326/0003-4819-88-3-433
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Published: Ann Intern Med. 1978;88(3):433-434.
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